The Influence of Different Solvents on the Interaction between Metal Ions and Tetracycline
نویسندگان
چکیده
The interaction o f the antibiotic tetracycline with a few metal ions, esp. Cu(II), in different so l vents has been investigated by means o f IR, ESR, and UV/VIS spectroscopy. It could be shown that the site o f complexation depends on the solvent used. In DM SO the interaction occurs mainly via the A ring. In water (pH = 5.7) and octanol, the A chromophore as well as the BCD entity o f the molecule are involved in complexation. If the tetracycline concentration exceeds the Cu(II) concentration, a 2 : 1 (antibiotic : Cu(II)) com plex seems to be formed, at least in DMSO.
منابع مشابه
Thermodynamic study of interaction between some transition metal ions and L-Alanine
Using UV-vis spectrophotometic method, the formation constants for interaction of Cd2+(aq) andCo2+(aq) ions with L-Alanine were experimentally studied at pH = 4.1 ± 0.01 (50mM of potassiumhydrogen phthalate buffer), ionic strength of 0.1M potassium nitrate and at 5 differenttemperatures 15,20, 25,30 and 35°C. The optical absorption spectra of mixtures containingconsidered cations and L-Alanine ...
متن کاملMetal ions binding study on human growth hormone by isothermal titration calorimetric method
The interaction of hGH with some metal ions ( ) at 27°C in NaC1 solution, 50 mM was studied using Isothermal titration calorimetry. There is a set of three identical and non-interacting binding sites for binding of all these metal ions, expect . The intrinsic association equilibrium constants () are not very different for and , and also their molar enthalpies of binding (KJ/mol for and KJ/mo...
متن کاملTheoretical study of the influence of solvent polarity on the structure and spectral properties in the interaction of C20 and Si2H2
In this investigation, the interaction of C20 and Si2H2 molecules was explored in the M06-2X/6-311++G(d,p)level of theory in gas solution phases. The obtained interaction energy values with standard method werecorrected by basis set superposition error (BSSE) during the geometry optimization for all molecules atthe same level of theory. Also, the bonding interaction between th...
متن کاملInteraction of some heavy metal ions with single walled carbon nanotube
The interaction between some heavy metal ions such as of Pb(II), Cd(II) and Cu(II) ions from aqueous solution adsorbed by single walled carbon nanotube (SWCNTs) and carboxylate group functionalized single walled carbon nanotube (SWCNT-COOH) surfaces were studied by atomic absorption spectroscopy. The effect of contact time, pH, initial concentration of ion, ionic strength and temperature on the...
متن کاملInteraction of some heavy metal ions with single walled carbon nanotube
The interaction between some heavy metal ions such as of Pb(II), Cd(II) and Cu(II) ions from aqueous solution adsorbed by single walled carbon nanotube (SWCNTs) and carboxylate group functionalized single walled carbon nanotube (SWCNT-COOH) surfaces were studied by atomic absorption spectroscopy. The effect of contact time, pH, initial concentration of ion, ionic strength and temperature on the...
متن کامل